Localization of leptin receptor mRNA expression in mouse brain

被引：146

作者：

Huang, XF

Koutcherov, I

Lin, S

Wang, HQ

Storlien, L

机构：

[1] Metabolic Research Center, Department of Biomedical Science, University of Wollongong

来源：

NEUROREPORT | 1996年 / 7卷 / 15-17期

关键词：

brain; leptin receptor; mouse; mRNA;

D O I：

10.1097/00001756-199611040-00045

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

THE distribution of the leptin receptor in the brain of C57 mice was investigated using a non-radioactive in situ hybridization method. Leptin receptor mRNA expression was highest in the arcuate nucleus and median eminence of the hypothalamus, but it was also abundant in hippocampus, primarily in the dentate gyrus and CA1, and was detected at low levels in piriform cortex and the medial margin of the medial habenular nucleus. The localization of leptin receptor-containing neurones in the present study indicates the possibility that the leptin receptor is expressed on neuropeptide Y-containing neurones.

引用

页码：2635 / 2638

页数：4

共 13 条

[1] RECOMBINANT MOUSE OB PROTEIN - EVIDENCE FOR A PERIPHERAL SIGNAL LINKING ADIPOSITY AND CENTRAL NEURAL NETWORKS [J].