An Abbreviated Montreal Cognitive Assessment (MoCA) for Dementia Screening

被引:81
作者
Horton, Daniel K. [1 ]
Hynan, Linda S. [1 ,2 ]
Lacritz, Laura H. [1 ,3 ]
Rossetti, Heidi C. [1 ]
Weiner, Myron F. [1 ,3 ]
Cullum, C. Munro [1 ,3 ]
机构
[1] Univ Texas SW Med Ctr Dallas, Dept Psychiat, Dallas, TX 75390 USA
[2] Univ Texas SW Med Ctr Dallas, Dept Clin Sci Biostat, Dallas, TX 75390 USA
[3] Univ Texas SW Med Ctr Dallas, Dept Neurol & Neurotherapeut, Dallas, TX 75390 USA
关键词
Short form; Montreal Cognitive Assessment; Mild cognitive impairment; Alzheimer's disease; Cognitive screening; MINI-MENTAL-STATE; PRIMARY-CARE; IMPAIRMENT; COG; VALIDATION; DIAGNOSIS; UTILITY; MMSE;
D O I
10.1080/13854046.2015.1043349
中图分类号
B849 [应用心理学];
学科分类号
040203 [应用心理学];
摘要
Objective: The Montreal Cognitive Assessment (MoCA) is a cognitive screening instrument growing in popularity, but few studies have conducted psychometric item analyses or attempted to develop abbreviated forms. We sought to derive and validate a short-form MoCA (SF-MoCA) and compare its classification accuracy to the standard MoCA and Mini-Mental State Examination (MMSE) in mild cognitive impairment (MCI), Alzheimer disease (AD), and normal aging. Methods: 408 subjects (MCI n=169, AD n=87, and normal n=152) were randomly divided into derivation and validation samples. Item analysis in the derivation sample identified most sensitive MoCA items. Receiver Operating Characteristic (ROC) analyses were used to develop cut-off scores and evaluate the classification accuracy of the SF-MoCA, standard MoCA, and MMSE. Net Reclassification Improvement (NRI) analyses and comparison of ROC curves were used to compare classification accuracy of the three measures. Results: Serial subtraction (Cramer's V=.408), delayed recall (Cramer's V=.702), and orientation items (Cramer's V=.832) were included in the SF-MoCA based on largest effect sizes in item analyses. Results revealed 72.6% classification accuracy of the SF-MoCA, compared with 71.9% for the standard MoCA and 67.4% for the MMSE. Results of NRI analyses and ROC curve comparisons revealed that classification accuracy of the SF-MoCA was comparable to the standard version and generally superior to the MMSE. Conclusions: Findings suggest the SF-MoCA could be an effective brief tool in detecting cognitive impairment.
引用
收藏
页码:413 / 425
页数:13
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