Computational fluid dynamic and magnetic resonance analyses of flow distribution between the lungs after total cavopulmonary connection

被引:36
作者
Migliavacca, F [1 ]
Kilner, PJ
Pennati, G
Dubini, G
Pietrabissa, R
Fumero, R
de Leval, MR
机构
[1] Politecn Milan, Dipartimento Bioingn, I-20133 Milan, Italy
[2] IRCCS San Raffaele, Milan, Italy
[3] Politecn Milan, CEBITEC, I-20133 Milan, Italy
[4] Royal Brompton Hosp, Magnet Resonance Unit, London SW3 6LY, England
[5] Politecn Milan, Dipartimento Energet, I-20133 Milan, Italy
[6] Great Ormond St Hosp Children, Cardiothorac Unit, NHS Trust, London WC1N 3JH, England
关键词
finite element method; computational fluid dynamics (CFD); congenital cardiac malformations; magnetic resonance (MR);
D O I
10.1109/10.752936
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Total cavopulmonary connection is a surgical procedure adopted to treat complex congenital malformations of the right heart, It consists basically in a connection of both venae cavae directly to the right pulmonary artery. In this paper a three-dimensional model of this connection is presented, which is based on in vivo measurements performed by means of magnetic resonance, The model was developed by means of computational fluid dynamics techniques, namely the finite element method. The aim of this study was to verify the capability of such a model to predict the distribution of the blood flow into the pulmonary arteries, by comparison with in vivo velocity measurements. Different simulations were performed on a single clinical case to test the sensitivity of the model to different boundary conditions, in terms of inlet velocity profiles as well as outlet pressure levels. Results showed that the how distribution between the lungs is slightly affected by the shape of inlet velocity profiles, whereas it is influenced by different pressure levels to a greater extent.
引用
收藏
页码:393 / 399
页数:7
相关论文
共 12 条
[1]   BAFFLE FENESTRATION WITH SUBSEQUENT TRANSCATHETER CLOSURE - MODIFICATION OF THE FONTAN OPERATION FOR PATIENTS AT INCREASED RISK [J].
BRIDGES, ND ;
LOCK, JE ;
CASTANEDA, AR .
CIRCULATION, 1990, 82 (05) :1681-1689
[2]   Use of computational fluid dynamics in the design of surgical procedures: Application to the study of competitive flows in cavopulmonary connections [J].
deLeval, MR ;
Dubini, G ;
Migliavacca, F ;
Jalali, H ;
Camporini, G ;
Redington, A ;
Pietrabissa, R .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1996, 111 (03) :502-510
[3]  
DELEVAL MR, 1988, J THORAC CARDIOV SUR, V96, P682
[4]  
Dubini G, 1996, J BIOMECH, V29, P839
[5]  
Jonas R A, 1988, J Card Surg, V3, P91, DOI 10.1111/j.1540-8191.1988.tb00228.x
[6]  
KROVETS LG, 1972, HOPKINS MED J, P130
[7]   POPULATION, RESOURCES, AND ENVIRONMENT - IMPLICATIONS OF HUMAN BEHAVIORAL ECOLOGY FOR CONSERVATION [J].
LOW, BS ;
HEINEN, JT .
POPULATION AND ENVIRONMENT, 1993, 15 (01) :7-41
[8]   FUNCTIONAL-ASPECTS OF CARDIOVASCULAR NUCLEAR-MAGNETIC-RESONANCE IMAGING - TECHNIQUES AND APPLICATION [J].
MOHIADDIN, RH ;
LONGMORE, DB .
CIRCULATION, 1993, 88 (01) :264-281
[9]   IN-VIVO STUDY OF AORTIC FLOW DISTURBANCES [J].
NEREM, RM ;
SEED, WA .
CARDIOVASCULAR RESEARCH, 1972, 6 (01) :1-&
[10]  
PUGA FJ, 1987, CIRCULATION, V76, P53