Neoamphimedine: A new pyridoacridine topoisomerase II inhibitor which catenates DNA

被引：41

作者：

de Guzman, FS

Carte, B

Troupe, N

Faulkner, DJ

Harper, MK

Concepcion, GP

Mangalindan, GC

Matsumoto, SS

Barrows, LR

Ireland, CM ^{[1
]}

机构：

[1] Univ Utah, Dept Med Chem, Salt Lake City, UT 84112 USA

[2] SmithKline Beecham Pharmaceut, King Of Prussia, PA 19406 USA

[3] Univ Calif San Diego, Scripps Inst Oceanog, La Jolla, CA 92093 USA

[4] Univ Utah, Dept Pharmacol & Toxicol, Salt Lake City, UT 84112 USA

[5] Univ Philippines, Inst Chem, Quezon City 1101, Philippines

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1999年 / 64卷 / 04期

关键词：

D O I：

10.1021/jo982047x

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

收藏

页码：1400 / 1402

页数：3

相关论文

共 8 条

[1] CATENATION AND KNOTTING OF DUPLEX DNA BY TYPE-1 TOPOISOMERASES - A MECHANISTIC PARALLEL WITH TYPE-2 TOPOISOMERASES
BROWN, PO
COZZARELLI, NR
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1981, 78 (02): : 843 - 847
[2] KRASNOW MA, 1982, J BIOL CHEM, V257, P2687
[3] KNOTTED SINGLE-STRANDED-DNA RINGS - NOVEL TOPOLOGICAL ISOMER OF CIRCULAR SINGLE-STRANDED-DNA FORMED BY TREATMENT WITH ESCHERICHIA-COLI OMEGA PROTEIN
LIU, LF
DEPEW, RE
WANG, JC
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1976, 106 (02) : 439 - 452
[4] MATSUMOTO SS, IN PRESS ANTICANCER
[5] MARINE PYRIDOACRIDINE ALKALOIDS - STRUCTURE, SYNTHESIS, AND BIOLOGICAL CHEMISTRY
MOLINSKI, TF
[J]. CHEMICAL REVIEWS, 1993, 93 (05) : 1825 - 1838
[6] AMPHIMEDINE, NEW AROMATIC ALKALOID FROM A PACIFIC SPONGE, AMPHIMEDON SP CARBON CONNECTIVITY DETERMINATION FROM NATURAL ABUNDANCE C-13-C-13 COUPLING-CONSTANTS
SCHMITZ, FJ
AGARWAL, SK
GUNASEKERA, SP
SCHMIDT, PG
SHOOLERY, JN
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (14) : 4835 - 4836
[7] CYTOTOXIC AROMATIC ALKALOIDS FROM THE ASCIDIAN AMPHICARPA-MERIDIANA AND LEPTOCLINIDES SP - MERIDINE AND 11-HYDROXYASCIDIDEMIN
SCHMITZ, FJ
DEGUZMAN, FS
HOSSAIN, MB
VANDERHELM, D
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (02) : 804 - 808
[8] ESCHERICHIA-COLI AND M-IUTEUS DNA TOPOISOMERASE I CAN CATALYZE CATENATION OR DECATENATION OF DOUBLE-STRANDED DNA RINGS
TSE, Y
WANG, JC
[J]. CELL, 1980, 22 (01) : 269 - 276