Terpenoid Synthases-From Chemical Ecology and Forest Fires to Biofuels and Bioproducts

被引:10
作者
Bohlmann, Joerg [1 ]
机构
[1] Univ British Columbia, Michael Smith Labs, Vancouver, BC V6T 1Z4, Canada
关键词
D O I
10.1016/j.str.2011.11.009
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Terpenoids are a diverse group of natural products with a myriad functions in ecological interactions of living organisms. Terpenoid synthases provide a unique reservoir of enzymes for the metabolic engineering of advanced biofuels and high-value bioproducts (McAndrew et al. in this issue of Structure).
引用
收藏
页码:1730 / 1731
页数:2
相关论文
共 11 条
[1]   Isoprenoid Pathway Optimization for Taxol Precursor Overproduction in Escherichia coli [J].
Ajikumar, Parayil Kumaran ;
Xiao, Wen-Hai ;
Tyo, Keith E. J. ;
Wang, Yong ;
Simeon, Fritz ;
Leonard, Effendi ;
Mucha, Oliver ;
Phon, Too Heng ;
Pfeifer, Blaine ;
Stephanopoulos, Gregory .
SCIENCE, 2010, 330 (6000) :70-74
[2]   Terpenoid-based defenses in conifers:: cDNA cloning, characterization, and functional expression of wound-inducible (E)-α-bisabolene synthase from grand fir (Abies grandis) [J].
Bohlmann, J ;
Crock, J ;
Jetter, R ;
Croteau, R .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (12) :6756-6761
[3]   Terpenoid biomaterials [J].
Bohlmann, Joerg ;
Keeling, Christopher I. .
PLANT JOURNAL, 2008, 54 (04) :656-669
[4]   Structural biology and chemistry of the terpenoid cyclases [J].
Christianson, David W. .
CHEMICAL REVIEWS, 2006, 106 (08) :3412-3442
[5]   The function of terpene natural products in the natural world [J].
Gershenzon, Jonathan ;
Dudareva, Natalia .
NATURE CHEMICAL BIOLOGY, 2007, 3 (07) :408-414
[6]   Identifying and manipulating structural determinates linking catalytic specificities in terpene synthases [J].
Greenhagen, Bryan T. ;
O'Maille, Paul E. ;
Noel, Joseph P. ;
Chappell, Joe .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2006, 103 (26) :9826-9831
[7]  
Köksal M, 2011, NAT CHEM BIOL, V7, P431, DOI [10.1038/nchembio.578, 10.1038/NCHEMBIO.578]
[8]   Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis [J].
Koeksal, Mustafa ;
Jin, Yinghua ;
Coates, Robert M. ;
Croteau, Rodney ;
Christianson, David W. .
NATURE, 2011, 469 (7328) :116-U138
[9]   Structure of a Three-Domain Sesquiterpene Synthase: A Prospective Target for Advanced Biofuels Production [J].
McAndrew, Ryan P. ;
Peralta-Yahya, Pamela P. ;
DeGiovanni, Andy ;
Pereira, Jose H. ;
Hadi, Masood Z. ;
Keesling, Jay D. ;
Adams, Paul D. .
STRUCTURE, 2011, 19 (12) :1876-1884
[10]   Identification and microbial production of a terpene-based advanced biofuel [J].
Peralta-Yahya, Pamela P. ;
Ouellet, Mario ;
Chan, Rossana ;
Mukhopadhyay, Aindrila ;
Keasling, Jay D. ;
Lee, Taek Soon .
NATURE COMMUNICATIONS, 2011, 2