The efficacy of dexmedetomidine in patients with noninvasive ventilation: A preliminary study

被引：68

作者：

Akada, Shinji ^{[1
]}

Takeda, Shinhiro ^{[1
]}

Yoshida, Yuko ^{[1
]}

Nakazato, Keiko ^{[1
]}

Mori, Masaki ^{[1
]}

Hongo, Takashi ^{[1
]}

Tanaka, Keiji ^{[1
]}

Sakamoto, Atsuhiro ^{[1
]}

机构：

[1] Nippon Med Sch, Dept Anesthesiol & Intens Care, Bunkyo Ku, Tokyo 1138603, Japan

来源：

ANESTHESIA AND ANALGESIA | 2008年 / 107卷 / 01期

关键词：

D O I：

10.1213/ane.0b013e3181732dc2

中图分类号：

R614 [麻醉学];

学科分类号：

100217 [麻醉学];

摘要：

BACKGROUND: Agitation is associated with failure of noninvasive ventilation (NIV). We investigated the effect of dexmedetomidine in patients with NIV. METHODS: This was a prospective clinical investigation in an intensive care unit. Dexmedetomidine was infused in 1.0 patients in whom NIV was difficult because of agitation. RESULTS: Ramsay and Richmond Agitation-Sedation Scale scores were maintained at 2.94 +/- 0.94 and -1.23 +/- 1.30, respectively. All patients were successfully weaned from NIV, and the respiratory state was not worsened. CONCLUSION: This study shows that dexmedetomidine is an effective sedative drug for patients with NIV.

引用

页码：167 / 170

页数：4

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