Sensing external stress:: watchdogs of the Escherichia coli cell envelope

被引:237
作者
Ruiz, N [1 ]
Silhavy, TJ [1 ]
机构
[1] Princeton Univ, Dept Mol Biol, Princeton, NJ 08544 USA
关键词
D O I
10.1016/j.mib.2005.02.013
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The Cpx and sigma(E) signaling systems monitor the cell envelope in Escherichia coli. When induced, each system triggers a signaling cascade that leads to the upregulation of factors needed to combat envelope damage. Although each system is distinct and can be uniquely induced by certain cues, they also share striking similarities. In this review, we discuss the recent progress in our understanding of the Cpx and sigma(E) systems and compare how both function to maintain the integrity of the cell envelope.
引用
收藏
页码:122 / 126
页数:5
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