Fatigue in MS is related to sympathetic vasomotor dysfunction

被引：103

作者：

Flachenecker, P

Rufer, A

Bihler, I

Hippel, C

Reiners, K

Toyka, KV

Kesselring, J

机构：

[1] Univ Wurzburg, Dept Neurol, D-97080 Wurzburg, Germany

[2] Rehabil Ctr Valens, Dept Neurol, Valens, Switzerland

来源：

NEUROLOGY | 2003年 / 61卷 / 06期

关键词：

D O I：

10.1212/01.WNL.0000080365.95436.B8

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors studied standard autonomic function tests and measures of heart rate variability in 60 patients with multiple sclerosis (MS) and correlated results with the Fatigue Severity Scale and the Modified Fatigue Impact Scale. The authors found that autonomic responses correlated with fatigue resembling a hypoadrenergic orthostatic response, possibly due to a sympathetic vasomotor lesion with intact vagal heart control. Treatments to control sympathetic dysfunction for MS-associated fatigue deserve further study.

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页码：851 / 853

页数：3

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