MitBASE: a comprehensive and integrated mitochondrial DNA database

被引:18
作者
Attimonelli, M [1 ]
Altamura, N
Benne, R
Boyen, C
Brennicke, A
Carone, A
Cooper, JM
D'Elia, D
de Montalvo, A
de Pinto, B
De Robertis, M
Golik, P
Grienenberger, JM
Knoop, V
Lanave, C
Lazowska, J
Lemagnen, A
Malladi, BS
Memeo, F
Monnerot, M
Pilbout, S
Schapira, AHV
Sloof, P
Slonimski, P
Stevens, K
Saccone, C
机构
[1] Univ Bari, Dipartmento Biochim & Biol Mol, I-70126 Bari, Italy
[2] CNR, Ctr Studio Mitocondri & Metab Energet, I-70126 Bari, Italy
[3] AMC Meibergdreef, Vakgrp Biochem, Amsterdam, Netherlands
[4] CNRS, Biol Stn, CEOBM, Roscoff, France
[5] Univ Ulm, D-89069 Ulm, Germany
[6] UCL, Royal Free & Univ Coll Med Sch, Univ Dept Clin Neurosci, London, England
[7] CNR, Area Ric, I-70126 Bari, Italy
[8] Univ Cantabria, Hosp Univ Marques de Valdecilla, Dept Biol Mol, Santander 39011, Spain
[9] CNRS, Ctr Genet Mol, F-91198 Gif Sur Yvette, France
[10] CNRS, Inst Biol Mol Plantes, F-67084 Strasbourg, France
[11] EBI Hinxton Hall, Cambridge, England
[12] Univ London, Inst Neurol, Dept Clin Neurol, London, England
关键词
D O I
10.1093/nar/27.1.128
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
MitBASE is an integrated and comprehensive database of mitochondrial DNA data which collects all available information from different organisms and from intraspecie variants and mutants. Research institutions from different countries are involved, each in charge of developing, collecting and annotating data for the organisms they are specialised in. The design of the actual structure of the database and its implementation in a user-friendly format are the care of the European Bioinformatics institute. The database can be accessed on the Web at the following address: http://www.ebi.ac. uk/htbin/Mitbase/mitbase.pl. The impact of this project is intended for both basic and applied research. The study of mitochondrial genetic diseases and mitochondrial DNA intraspecie diversity are key topics in several biotechnological fields. The database has been funded within the EU Biotechnology programme.
引用
收藏
页码:128 / 133
页数:6
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