Ti(NMe2)4 as a precatalyst for hydroamination of alkynes with primary amines

被引：152

作者：

Shi, YH ^{[1
]}

Ciszewski, JT ^{[1
]}

Odom, AL ^{[1
]}

机构：

[1] Michigan State Univ, Dept Chem, E Lansing, MI 48824 USA

来源：

ORGANOMETALLICS | 2001年 / 20卷 / 19期

关键词：

D O I：

10.1021/om010566b

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Hydroaminations of carbon-carbon triple bonds with primary amines are catalyzed with commercially available Ti(NMe2)(4). The reaction is surprisingly fast with many substrates and often selective for the Markovnikov product with terminal alkynes. The scope of the catalysis was investigated with a variety of amines and alkynes; arylamines and 1-hexyne were found to be especially good substrates.

引用

页码：3967 / 3969

页数：3

共 24 条

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