Detection of binary-toxin genes (cdtA and cdtB) among Clostridium difficile strains isolated from patients with C-difficile-associated diarrhoea (CDAD) in Poland

被引：27

作者：

Pituch, H

Rupnik, M

Obuch-Woszczatynski, P

Grubesic, A

Meisel-Mikolajczyk, F

Luczak, M

机构：

[1] Med Univ Warsaw, Dept Med Microbiol, PL-02004 Warsaw, Poland

[2] Univ Ljubljana, Dept Biol, Ljubljana, Slovenia

来源：

JOURNAL OF MEDICAL MICROBIOLOGY | 2005年 / 54卷 / 02期

关键词：

D O I：

10.1099/jmm.0.45799-0

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Clostridium difficile A(+)B(+) and A(-)B(+) strains isolated from stool samples of patients with C. difficile-associated diarrhoea (CDAD) were selected from the University Hospital Warsaw collection. The binary-toxin genes cdtA and cdtB were detected by PCR in five of the 41 A(+)B(+) strains tested, but in none of the 17 A(-)B(+) strains tested, giving 8-6% prevalence (5/58) of binary-toxin-positive strains. All of the strains that were positive for binary-toxin genes were grouped into toxinotype IV, suggesting that in this institution toxinotype IV might dominate among the population of C. difficile with binary-toxin genes.

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页码：143 / 147

页数：5

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