The pathophysiology of photosensitivity in lupus erythematosus

被引：28

作者：

Orteu, CH ^{[1
]}

Sontheimer, RD ^{[1
]}

Dutz, JP ^{[1
]}

机构：

[1] Univ British Columbia, Fac Med, Div Dermatol, Vancouver, BC V5Z 4E8, Canada

来源：

PHOTODERMATOLOGY PHOTOIMMUNOLOGY & PHOTOMEDICINE | 2001年 / 17卷 / 03期

关键词：

lupus erythematosus; photosensitivity; apoptosis; TNF alpha; heat shock protein;

D O I：

10.1034/j.1600-0781.2001.170301.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

The strong association between photosensitivity and lupus erythematosus has led to the suggestion that abnormal photoreactivity participates in the pathogenesis of cutaneous lesions. In this review we discuss the evidence for abnormal cutaneous reactivity to sunlight in lupus and speculate on the cellular, molecular and genetic factors that may underlie this abnormality.

引用

页码：95 / 113

页数：19

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