Proteomic analysis of peritoneal fluid in women with endometriosis

被引：48

作者：

Ferrero, Simone

Gillott, David J.

Remorgida, Valentino

Anserini, Paola

Leung, Kit-Yi

Ragni, Nicola

Grudzinskas, Jurgis G.

机构：

[1] Queen Mary Univ London, St Bartholomews Sch Med & Dent, Reprod Physiol Lab, London, England

[2] Univ Genoa, St Marino Hosp, Dept Obstet & Gynaecol, I-16126 Genoa, Italy

[3] Queen Mary Univ London, William Harvey Res Inst, London, England

来源：

JOURNAL OF PROTEOME RESEARCH | 2007年 / 6卷 / 09期

关键词：

endometriosis; peritoneal fluid; tandem mass spectrometry; proteomics; two-dimensional gel; electrophoresis;

D O I：

10.1021/pr060680q

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

This study aims to evaluate differences in the expression of proteins present in the peritoneal fluid (PF) of women with and without endometriosis. PF samples were subjected to two-dimensional gel electrophoresis; protein spots of interest were identified by liquid chromatography tandem mass spectrometry. Several molecules had aberrant expression in PF of women with endometriosis; they may be useful for a better understanding of the pathogenesis of this disease.

引用

页码：3402 / 3411

页数：10

共 61 条

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