The link between knowledge and remembering in Alzheimer's disease

被引:14
作者
Backman, L
机构
[1] Univ Gothenburg, Dept Psychol, S-41314 Gothenburg, Sweden
[2] Stockholm Gerontol Res Ctr, Stockholm, Sweden
[3] Karolinska Inst, Dept Clin Neurosci & Family Med, Sect Geriatr, Stockholm, Sweden
关键词
knowledge; memory; Alzheimer's disease; cognitive support;
D O I
10.1111/1467-9450.393067
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
Current research on the influence of cognitive support (e.g., activation of task-relevant prior knowledge, item organizability, retrieval cues) on episodic remembering in normal aging and Alzheimer's disease (AD) is reviewed. Examining the effects of cognitive support on memory may shed light on the relationship between knowledge and remembering, and also provides relevant information pertaining to the development of cognitive intervention procedures. A series of studies from our own and other laboratories reveal a number of interesting empirical regularities. First, AD results in problems in utilizing cognitive support for improving memory. Conceivably, this reduction in cognitive reserve capacity is due to both the overall severity of the episodic memory impairment in AD, as well as to dementia-related deficits in the semantic network that guides encoding and retrieval of information. Nevertheless, AD patients are able to utilize cognitive support in episodic memory tasks, although they typically need more support than their healthy aged counterparts to show memory facilitation. Specifically, it is critical to provide support at both encoding and retrieval in order to demonstrate performance gains in AD. Moreover, successful utilization of retrieval support in this disease is most likely to occur when the encoding requirements force the individual to engage in elaborative cognitive activity (e.g., generation of task-relevant knowledge, categorical organization). Finally, a reduction in cognitive reserve capacity occurs later in the pathogenesis of AD than a generalized episodic memory impairment. This observation reflects the insidious nature of AD, and suggests that the transition from normal aging to AD may be continuous rather than discrete.
引用
收藏
页码:131 / 139
页数:9
相关论文
共 57 条
[1]  
ALMKVIST O, 1998, UNPUB SIMILAR PATTER
[2]  
[Anonymous], THEORY COGNITIVE AGI
[3]  
[Anonymous], SUCCESSFUL AGING PER
[4]  
[Anonymous], 1996, COGNITIVE NEUROPSYCH
[5]  
[Anonymous], 1988, HUMAN ORGANIC MEMORY
[6]  
Backman L, 1998, PSYCHOL AGING, V13, P267
[7]   Brain activation in young and older adults during implicit and explicit retrieval [J].
Backman, L ;
Almkvist, O ;
Andersson, J ;
Nordberg, A ;
Winblad, B ;
Reineck, R ;
Langstrom, B .
JOURNAL OF COGNITIVE NEUROSCIENCE, 1997, 9 (03) :378-391
[8]  
BACKMAN L, 1989, EVERYDAY COGNITION IN ADULTHOOD AND LATE LIFE, P509
[9]   Influences of item organizability and semantic retrieval cues on word recall in very old age [J].
Backman, L ;
Wahlin, A .
AGING AND COGNITION, 1995, 2 (04) :312-325
[10]  
BACKMAN L, 1994, ANN PSYCHIAT, V4, P57