A general, Bronsted acid-catalyzed hetero-Michael addition of nitrogen, oxygen, and sulfur nucleophiles

被引：204

作者：

Wabnitz, TC ^{[1
]}

Spencer, JB ^{[1
]}

机构：

[1] Univ Cambridge, Chem Lab, Cambridge CB2 1EW, England

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 12期

关键词：

D O I：

10.1021/ol034596h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Strong Bronsted acids such as bis(trifluoromethariesulfon)imide catalyze the hetero-Michael addition of carbamates, alcohols, and thiols to alpha,beta-unsaturated ketones, alkylidene malonates, and acrylimides. Scope, reaction rates, and yields are superior to comparable Lewis acid-catalyzed processes.

引用

页码：2141 / 2144

页数：4

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