New TEM variant (TEM-92) produced by Proteus mirabilis and Providencia stuartii isolates

被引：23

作者：

De Champs, C

Monne, C

Bonnet, R

Sougakoff, W

Sirot, D

Chanal, C

Sirot, J

机构：

[1] Fac Med, Bacteriol Lab, F-63001 Clermont Ferrand, France

[2] Univ Paris 06, Lab Bacteriol Hyg, F-75634 Paris 13, France

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 04期

关键词：

D O I：

10.1128/AAC.45.4.1278-1280.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The sequences of the bla.,,, genes encoding TEM-92 in Proteus mirabilis and Providencia stuartii isolates were determined and were found to be identical, Except for positions 218 (Lys-6) and 512 (Lys-104), the nucleotide sequence of bla(TEM-92) was identical to that of bla(TEM-20) including the sequence of the promoter region harboring a 135-bp deletion combined with a G-162 -->T substitution, The deduced amino acid sequence of TEM-92 differed from that of TEM-52 by the presence of a substitution (Gln-6 --> Lys) in the peptide signal.

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页码：1278 / 1280

页数：3

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