Morphinome - proteome of the nervous system after morphine treatment

被引:11
作者
Bodzon-Kulakowska, A
Bierczynska-Krzysik, A
Drabik, A
Noga, M
Kraj, A
Suder, P
Silberring, J [1 ]
机构
[1] Jagiellonian Univ, Fac Chem, Dept Neurobiochem, Ingardena St 3, PL-30060 Krakow, Poland
[2] Jagiellonian Univ, Coll Med, Inst Med Biochem, PL-30060 Krakow, Poland
[3] Jagiellonian Univ, Reg Lab, Krakow, Poland
[4] Polish Acad Sci, Ctr Polymer Chem, PL-41800 Zabrze, Poland
关键词
morphine; dependence; cell culture; brain; nervous system; proteome; proteins; analysis; peptide map; sequence; mass spectrometry; electrophoresis;
D O I
10.1007/s00726-004-0144-y
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Proteome is a natural consequence of the post-genome era when the HUGO project ( Human Genome Organization) has almost been completed. Here, a specifically aimed proteome in drug dependence morphinome, is described, including tasks, strategies and pitfalls of the methodology.
引用
收藏
页码:13 / 19
页数:7
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