Is the MCM2-7 complex the eukaryotic DNA replication fork helicase?

被引：127

作者：

Labib, K ^{[1
]}

Diffley, JF ^{[1
]}

机构：

[1] Imperial Canc Res Fund, Clare Hall Labs, Chromosome Replicat Lab, S Mimms EN6 3LD, Herts, England

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2001年 / 11卷 / 01期

关键词：

D O I：

10.1016/S0959-437X(00)00158-1

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The MCM2-7 complex is essential for both the initiation and elongation phases of eukaryotic chromosome replication. There is some evidence that MCM2-7 proteins may act as a DNA helicase; at the same time, a variety of other DNA helicases have also been implicated in the replication of eukaryotic chromosomes.

引用

页码：64 / 70

页数：7

共 66 条

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