Projections from the ventrolateral periaqueductal gray to endocrine regulatory subdivisions of the paraventricular nucleus of the hypothalamus in the rat

被引：38

作者：

Floyd, NS

Keay, KA

Arias, CM

Sawchenko, PE

Bandler, R

机构：

[1] UNIV SYDNEY,DEPT ANAT & HISTOL,SYDNEY,NSW 2006,AUSTRALIA

[2] UNIV SYDNEY,INST BIOMED RES,SYDNEY,NSW 2006,AUSTRALIA

[3] SALK INST BIOL STUDIES,NEURONAL STRUCT & FUNCT LAB,LA JOLLA,CA 92037

来源：

NEUROSCIENCE LETTERS | 1996年 / 220卷 / 02期

关键词：

pain; haemorrhage; injury; emotion; hypotension; vasopressin; adrenocorticotrophic hormone;

D O I：

10.1016/S0304-3940(96)13240-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The ventrolateral periaqueductal gray (vlPAG) mediates quiescence, hyporeactivity, hypotension and bradycardia, a pattern of response evoked by injury or social defeat. These stimuli also evoke increased levels of vasopressin (VP) and adrenocorticotrophic hormone (ACTH). A key central nervous system (CNS) locus mediating endocrine changes is the paraventricular nucleus of the hypothalamus (PVH). We investigated the extent of vlPAG projections to PVH. Anterograde tracer injections into the vlPAG, revealed 'terminal' label in: (1) the medial, dorsal, anterior and lateral parvicellular divisions, and (2) lateral and medial posterior magnocellular divisions of the PVH. Deposits of the retrograde tracer Fast Blue, verified the projection to the PVH arising from the vlPAG. Copyright (C) 1996 Elsevier Science Irelan Ltd.

引用

页码：105 / 108

页数：4

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