The Medicago Genome Initiative:: a model legume database

被引:100
作者
Bell, CJ
Dixon, RA
Farmer, AD
Flores, R
Inman, J
Gonzales, RA
Harrison, MJ
Paiva, NL
Scott, AD
Weller, JW
May, GD
机构
[1] Samuel Roberts Noble Fdn Inc, Div Plant Biol, Ardmore, OK 73402 USA
[2] Natl Ctr Genome Resources, Santa Fe, NM 87505 USA
[3] Virginia Bioinformat Inst, Blacksburg, VA 24061 USA
关键词
D O I
10.1093/nar/29.1.114
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The Medicago Genome Initiative (MGI) is a database of EST sequences of the model legume Medicago truncatula. The database is available to the public and has resulted from a collaborative research effort between the Samuel Roberts Noble Foundation and the National Center for Genome Resources to investigate the genome of M.truncatula. MGI is part of the greater integrated Medicago functional genomics program at the Noble Foundation (http://www.noble.org), which is taking a global approach in studying the genetic and biochemical events associated with the growth, development and environmental interactions of this model legume. Our approach will include: large-scale EST sequencing, gene expression profiling, the generation of M.truncatula activation-tagged and promoter trap insertion mutants, high-throughput metabolic profiling, and proteome studies. These multidisciplinary information pools will be interfaced with one another to provide scientists with an integrated, holistic set of tools to address fundamental questions pertaining to legume biology. The public interface to the MGI database can be accessed at http://www.ncgr.org/research/mgi.
引用
收藏
页码:114 / 117
页数:4
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