Aptamer biosensor for label-free impedance spectroscopy detection of proteins based on recognition-induced switching of the surface charge

被引:293
作者
Rodriguez, MC
Kawde, AN
Wang, J [1 ]
机构
[1] Arizona State Univ, Dept Chem & Mat Engn, Biodesign Inst, Tempe, AZ 85287 USA
[2] Arizona State Univ, Dept Chem & Biochem, Biodesign Inst, Tempe, AZ 85287 USA
基金
美国国家科学基金会;
关键词
D O I
10.1039/b506571b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The recognition of proteins by aptamer-modified electrode transducers reverses the surface charge and leads to a novel label-free impedance spectroscopy bioelectronic detection protocol based on a decrease in the electron transfer resistance.
引用
收藏
页码:4267 / 4269
页数:3
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