Linezolid:: pharmacokinetic characteristics and clinical studies

被引：37

作者：

Bouza, E ^{[1
]}

Muñoz, P ^{[1
]}

机构：

[1] Hosp Gen Univ Gregorio Maranon, Clin Microbiol & Infect Dis Dept, Madrid 28007, Spain

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2001年 / 7卷

关键词：

D O I：

10.1046/j.1469-0691.2001.00061.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Linezolid is an oxazolidinone indicated in the treatment of nosocomial and community-acquired pneumonia, complicated and uncomplicated skin and skin structure infections and vancomycin-resistant Enterococcus infections. The drug is also approved for use in complicated skin infections and nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus, concurrent bacteremia associated with vancomycin-resistant Enterococcus faecium and concurrent bacteremia associated with community-acquired pneumonia caused by penicillin-susceptible Streptococcus pneumoniae.

引用

页码：75 / 82

页数：8

共 42 条

[1] Methicillin-resistant Staphylococcus aureus infection in a renal allograft recipient treated successfully with a novel new antimicrobial agent (Linezolid):: New treatment options for infections due to resistant organisms
Antony, SJ
Bitter, KM
Moreland, T
Raudales, F
Diaz-Luna, H
[J]. CLINICAL INFECTIOUS DISEASES, 1999, 29 (05) : 1341 - 1342
[2] Therapy for Pneumococcal Infection at the Millennium: Doubts and Certainties
Ball, Peter
[J]. AMERICAN JOURNAL OF MEDICINE, 1999, 107 (01) : 77 - 85
[3] Identification of a novel oxazolidinone (U-100480) with potent antimycobacterial activity
Barbachyn, MR
Hutchinson, DK
Brickner, SJ
Cynamon, MH
Kilburn, JO
Klemens, SP
Glickman, SE
Grega, KC
Hendges, SK
Toops, DS
Ford, CW
Zurenko, GE
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (03) : 680 - 685
[4] Barrett J F, 2000, Curr Opin Investig Drugs, V1, P181
[5] BIRMINGHAM MC, 2000, 40 INT C ANT AG CHEM, P488
[6] Brier ME, 1998, J INVEST MED, V46, p276A
[7] CAMMARATA SK, 2000, 40 INT C ANT AG CHEM
[8] CAMMARATA SK, 2001, AM J RESP CRIT CAR S, V161, pA654
[9] Cammarata SK, 2000, EUR RESPIR J, V16, p139S
[10] Cammarata SK, 2000, CLIN MICROBIOL INFEC, V6, P136

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