Nucleophilic and radical chemistry of benzylselenides: preparation of novel selenocephems and selenopenams

被引：19

作者：

Carland, MW ^{[1
]}

Martin, RL ^{[1
]}

Schiesser, CH ^{[1
]}

机构：

[1] Univ Melbourne, Sch Chem, Melbourne, Vic 3010, Australia

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 28期

基金：

澳大利亚研究理事会;

关键词：

D O I：

10.1016/S0040-4039(01)00826-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Selenocephems (14 and 15) and selenopenams (18, 20, 24 and 25) can be prepared in 18-85% yields through the intramolecular homolytic substitution of aryl or alkyl radicals at the selenium atom in suitably-substituted 4-benzylseleno-beta -lacrams, ol through intramolecular nucleophilic substitution by the benzylseleno moiety in 4-halo-beta -lactam precursors. (C) 2001 Elsevier Science Ltd. All lights reserved.

引用

页码：4737 / 4739

页数：3

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