Scaling properties of a low-actuation pressure microfluidic valve

被引:228
作者
Studer, V [1 ]
Hang, G
Pandolfi, A
Ortiz, M
Anderson, WF
Quake, SR
机构
[1] CALTECH, Dept Appl Phys, Pasadena, CA 91125 USA
[2] Politecn Milan, Dipartimento Ingn Strutturale, I-20133 Milan, Italy
[3] CALTECH, Grad Aeronaut Labs, Pasadena, CA 91125 USA
[4] Univ So Calif, Keck Sch Med, Gene Therapy Labs, Los Angeles, CA 90033 USA
关键词
D O I
10.1063/1.1629781
中图分类号
O59 [应用物理学];
学科分类号
摘要
Using basic physical arguments, we present a design and method for the fabrication of microfluidic valves using multilayer soft lithography. These on-off valves have extremely low actuation pressures and can be used to fabricate active functions, such as pumps and mixers in integrated microfluidic chips. We characterized the performance of the valves by measuring both the actuation pressure and flow resistance over a wide range of design parameters, and compared them to both finite element simulations and alternative valve geometries. (C) 2004 American Institute of Physics.
引用
收藏
页码:393 / 398
页数:6
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