1,3-dipolar cycloaddition reactions of isothiazol-3(2H)-ones with nitrile oxides. An unexpected site selectivity of the carbonyl bond of 5-benzoyl-isothiazol-3(2H)-one

被引：10

作者：

CoutouliArgyropoulou, E

Anastasopoulos, C

机构：

[1] Laboratory of Organic Chemistry, University of Thessaloniki, Thessaloniki

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1996年 / 33卷 / 03期

关键词：

D O I：

10.1002/jhet.5570330335

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2,6-Dichlorobenzonitrile oxide (2a) reacts with isothiazolones 1a and 1b at the ethylenic double bond to give 4 via transformation of the primary cycloadducts 3. Mesitonitrile oxide (2b) adds preferentially to the carbonyl double bond of 1b yielding the monoadduct 5 and the bisadduct 6.

引用

页码：731 / 733

页数：3

共 20 条

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