Glycoprotein IIb/IIIa inhibitors in patients with unstable angina/non-ST-segment elevation myocardial infarction: Appropriate interpretation of the guidelines

被引:9
作者
Antman, EM [1 ]
机构
[1] Harvard Univ, Sch Med, Boston, MA 02115 USA
[2] Brigham & Womens Hosp, Samuel A Levine Cardiac Unit, Coronary Care Unit, Boston, MA 02115 USA
关键词
D O I
10.1016/j.ahj.2003.09.001
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In 2002, the American College of Cardiology and the American Heart Association published an update to their guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction. These revised guidelines make specific recommendations regarding the use of glycoprotein IIb/IIIa inhibitors. This article briefly reviews the evidence supporting the use of glycoprotein IIb/IIIa inhibitors in unstable angina and non-ST-segment elevation myocardial infarction, before moving on to discuss interpretation of these new guidelines.
引用
收藏
页数:5
相关论文
共 11 条
  • [1] CD40L stabilizes arterial thrombi by a β3 integrin-dependent mechanism
    André, P
    Prasad, KSS
    Denis, CV
    He, M
    Papalia, JM
    Hynes, RO
    Phillips, DR
    Wagner, DD
    [J]. NATURE MEDICINE, 2002, 8 (03) : 247 - 252
  • [2] 'I can see clearly now': a new view on the use of IV GP IIb/IIIa inhibitors in acute coronary syndromes
    Antman, EM
    [J]. EUROPEAN HEART JOURNAL, 2002, 23 (18) : 1408 - 1411
  • [3] Platelet glycoprotein IIb/IIIa receptor inhibition in non-ST-elevation acute coronary syndromes -: Early benefit during medical treatment only, with additional protection during percutaneous coronary intervention
    Boersma, E
    Akkerhuis, KM
    Théroux, P
    Califf, RM
    Topol, EJ
    Simoons, ML
    [J]. CIRCULATION, 1999, 100 (20) : 2045 - 2048
  • [4] Platelet glycoprotein IIb/IIIa inhibitors in acute coronary syndromes:: a meta-analysis of all major randomised clinical trials
    Boersma, E
    Harrington, RA
    Moliterno, DJ
    White, H
    Théroux, P
    Van de Werf, F
    de Torbal, A
    Armstrong, PW
    Wallentin, LC
    Wilcox, RG
    Simes, J
    Califf, RM
    Topol, EJ
    Simoons, ML
    [J]. LANCET, 2002, 359 (9302) : 189 - 198
  • [5] Invasive versus conservative strategies in unstable angina and non-Q-wave myocardial infarction following treatment with tirofiban:: Rationale and study design of the international TACTICS-TIMI 18 trial
    Cannon, CP
    Weintraub, WS
    Demopoulos, LA
    Robertson, DH
    Gormley, GJ
    Braunwald, E
    [J]. AMERICAN JOURNAL OF CARDIOLOGY, 1998, 82 (06) : 731 - 736
  • [6] *COMM MAN PAT UNST, 2002, J AM COLL CARDIOL, V40, P1366
  • [7] CD40 signaling in vascular cells:: A key role in atherosclerosis?
    Mach, F
    Schönbeck, U
    Libby, P
    [J]. ATHEROSCLEROSIS, 1998, 137 : S89 - S95
  • [8] Inhibitory effects of glycoprotein IIb/IIIa antagonists and aspirin on the release of soluble CD40 ligand during platelet stimulation
    Nannizzi-Alaimo, L
    Alves, VL
    Phillips, DR
    [J]. CIRCULATION, 2003, 107 (08) : 1123 - 1128
  • [9] Platelet glycoprotein IIb/IIIa inhibitors - Recognition of a two-edged sword?
    Quinn, MJ
    Plow, EF
    Topol, EJ
    [J]. CIRCULATION, 2002, 106 (03) : 379 - 385
  • [10] Platelet glycoprotein IIb/IIIa inhibition in acute coronary syndromes -: Gradient of benefit related to the revascularization strategy
    Roffi, M
    Chew, DP
    Mukherjee, D
    Bhatt, DL
    White, JA
    Moliterno, DJ
    Heeschen, C
    Hamm, CW
    Robbins, MA
    Kleiman, NS
    Théroux, P
    White, HD
    Topol, EJ
    [J]. EUROPEAN HEART JOURNAL, 2002, 23 (18) : 1441 - 1448