Palladium-catalyzed acylation reactions of α,β-unsaturated ketones with acylzirconocene chloride:: Remarkable control of 1,2- and 1,4-selectivity by the catalyst

被引：30

作者：

Hanzawa, Y ^{[1
]}

Tabuchi, N ^{[1
]}

Taguchi, T ^{[1
]}

机构：

[1] Tokyo Univ Pharm & Life Sci, Sch Pharm, Tokyo 1920392, Japan

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 44期

关键词：

acylation; Michael reactions; palladium and compounds; zirconium and compounds;

D O I：

10.1016/S0040-4039(98)01807-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed reactions of alpha,beta-unsaturated ketones with acylzirconocene chloride showed not only an efficient acyl transfer to alpha,beta-unsaturated ketones but also a remarkable regiochemical control by selecting PdCl2(Ph-3)(2) or Pd(OAc)(2). (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：8141 / 8144

页数：4