Structure-activity relationships for selected sulfur-rich antifungal compounds

被引：26

作者：

Baerlocher, FJ ^{[1
]}

Langler, RF

Fredriksen, MU

Georges, NM

Witherell, RD

机构：

[1] Mt Allison Univ, Dept Biol, Sackville, NB E4L 1G7, Canada

[2] Mt Allison Univ, Dept Chem, Sackville, NB E4L 1G8, Canada

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 1999年 / 52卷 / 03期

关键词：

D O I：

10.1071/C98141

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A series of sulfur compounds has been prepared and tested against two kinds of fungi: Aspergillus niger and Aspergillus flavus. Results on various sulfone disulfides and ester disulfides have led to the formulation of a proposed mechanism for fungicidal behaviour that permits one to anticipate which structures will be antifungal.

引用

页码：167 / 172

页数：6

共 56 条

[1] Synthesis and chlorination of chloromethyl methylsulfonylmethyl sulfide [J].

Ahern, TP ;

Hennigar, TL ;

MacDonald, JA ;

Morrison, HG ;

Langler, RF ;

Satyanarayana, S ;

Zaworotko, MJ .

AUSTRALIAN JOURNAL OF CHEMISTRY, 1997, 50 (06) :683-687

[2] THE SYNTHESIS AND CHLORINOLYSIS OF 5-PHENYL-2,4,5-TRITHIAPENTANE-2,2-DIOXIDE [J].

AHERN, TP ;

LANGLER, RF ;

MCNEIL, RL .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1980, 58 (18) :1996-1998

[3] MECHANISMS IN THE CHLORINOLYSIS OF SULFINYL CHLORIDES [J].

AHERN, TP ;

HALEY, MF ;

LANGLER, RF ;

TRENHOLM, JE .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1984, 62 (03) :610-614

[4]

AKISUE M K, 1984, Revista de Farmacia e Bioquimica da Universidade de Sao Paulo, V20, P145

[5] CERTAIN PHYSICAL PROPERTIES OF SOME SUBSTITUTED DIPHENYL SULFONES AND SULFOXIDES [J].

AMSTUTZ, ED ;

CHESSICK, JJ ;

HUNSBERGER, IM .

SCIENCE, 1950, 111 (2882) :305-307

[6] A SHORT SYNTHESIS OF THE ANTIFUNGAL PRINCIPLE OF SAPIUM-JAPONICUM [J].

BACK, TG ;

DYCK, BP .

TETRAHEDRON LETTERS, 1992, 33 (33) :4725-4726

[7] BIOLOGICALLY-ACTIVE VOLATILE ORGANOSULFUR COMPOUNDS FROM SEEDS OF THE NEEM TREE, AZADIRACHTA-INDICA (MELIACEAE) [J].

BALANDRIN, MF ;

LEE, SM ;

KLOCKE, JA .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1988, 36 (05) :1048-1054

[8] REDUCTION STUDIES OF ANTIFUNGAL ECHINOCANDIN LIPOPEPTIDES - ONE-STEP CONVERSION OF ECHINOCANDIN-B TO ECHINOCANDIN-C [J].

BALKOVEC, JM ;

BLACK, RM .

TETRAHEDRON LETTERS, 1992, 33 (32) :4529-4532

[9] SIMPLE TOTAL SYNTHESES OF BIOLOGICALLY-ACTIVE PENTATHIADECANE NATURAL-PRODUCTS, 2,4,5,7,9-PENTATHIADECANE 2,2,9,9-TETRAOXIDE (DYSOXYSULFONE), FROM DYSOXYLUM-RICHII, AND 2,3,5,7,9-PENTATHIADECANE 9,9-DIOXIDE, THE MISIDENTIFIED LENTHIONINE PRECURSOR SE-3 FROM SHIITAKE MUSHROOM (LENTINUS-EDODES) [J].

BLOCK, E ;

DEORAZIO, R ;

THIRUVAZHI, M .

JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (09) :2273-2275

[10] ALPHA-DISULFIDE CARBONIUM-IONS [J].

BLOCK, E .

JOURNAL OF ORGANIC CHEMISTRY, 1974, 39 (05) :734-736

← 1 2 3 4 5 6 →