PPL-catalysed hydrolysis of 3,4-disubstituted β-lactams:: Effect of chain length and stereochemistry on the enantioselectivity

被引：30

作者：

Basak, A ^{[1
]}

Bhattacharya, G ^{[1
]}

Bdour, HMM ^{[1
]}

机构：

[1] Indian Inst Technol, Dept Chem, Kharagpur 721302, W Bengal, India

来源：

TETRAHEDRON | 1998年 / 54卷 / 23期

关键词：

D O I：

10.1016/S0040-4020(98)00313-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3,4-Disubstituted beta-lactam acetates 1a-15a have been subjected to PPL-catalysed hydrolysis. The stereochemical course of hydrolysis has been shown to depend upon the C3-C4 relative stereochemistry and the length of the chain bearing acetate functionality. (C) 1998 Published by Elsevier Science Ltd. All rights reserved.

引用

页码：6529 / 6538

页数：10

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