Matrix-induced response enhancement in pesticide residue analysis by gas chromatography

被引:209
作者
Poole, Colin F. [1 ]
机构
[1] Wayne State Univ, Dept Chem, Detroit, MI 48202 USA
关键词
gas chromatography; pesticide analysis; matrix-induced response enhancement; calibration; standard addition;
D O I
10.1016/j.chroma.2007.01.018
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The sample matrix can cause an enhancement in the observed chromatographic response for pesticide residues in a matrix extract compared with the same concentration in a matrix-free solution. The matrix increases the transfer of pesticides from hot vaporizing injectors by reducing the thermal stress for labile compounds and by masking active sites in the injector responsible for the adsorption or decomposition of polar pesticides. The use of different injector types and matrix simplification procedures can reduce matrix-induced enhancement but do not eliminate it. The most effective strategy is to use matrix-matched calibration standards or analyte protectants which equalize the response enhancement for calibration standards and sample extracts. From a practical point of view it is important that the method used to correct for matrix-induced enhancement is compatible with low system maintenance. The different approaches for correcting matrix-induced enhancement for calibration in pesticide residue analysis are discussed and compared in this review. (c) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:241 / 250
页数:10
相关论文
共 67 条