Causal Inference for Definitive Clinical End Points in a Randomized Clinical Trial With Intervening Nonrandomized Treatments

被引:6
作者
Korn, Edward L. [1 ]
Freidlin, Boris [1 ]
机构
[1] NCI, Bethesda, MD 20892 USA
关键词
RENAL-CELL CARCINOMA; PHASE-III TRIAL; CANCER; EFFICACY;
D O I
10.1200/JCO.2010.30.0442
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:3800 / 3802
页数:4
相关论文
共 11 条
[1]   Estimating a treatment effect in survival studies in which patients switch treatment [J].
Branson, M ;
Whitehead, J .
STATISTICS IN MEDICINE, 2002, 21 (17) :2449-2463
[2]   Sorafenib for Treatment of Renal Cell Carcinoma: Final Efficacy and Safety Results of the Phase III Treatment Approaches in Renal Cancer Global Evaluation Trial [J].
Escudier, Bernard ;
Eisen, Tim ;
Stadler, Walter M. ;
Szczylik, Cezary ;
Oudard, Stephane ;
Staehler, Michael ;
Negrier, Sylvie ;
Chevreau, Christine ;
Desai, Apurva A. ;
Rolland, Frederic ;
Demkow, Tomasz ;
Hutson, Thomas E. ;
Gore, Martin ;
Anderson, Sibyl ;
Hofilena, Gloria ;
Shan, Minghua ;
Pena, Carol ;
Lathia, Chetan ;
Bukowski, Ronald M. .
JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (20) :3312-3318
[3]   Trastuzumab Plus Anastrozole Versus Anastrozole Alone for the Treatment of Postmenopausal Women With Human Epidermal Growth Factor Receptor 2-Positive, Hormone Receptor-Positive Metastatic Breast Cancer: Results From the Randomized Phase III TAnDEM Study [J].
Kaufman, Bella ;
Mackey, John R. ;
Clemens, Michael R. ;
Bapsy, Poonamalle P. ;
Vaid, Ashok ;
Wardley, Andrew ;
Tjulandin, Sergei ;
Jahn, Michaela ;
Lehle, Michaela ;
Feyereislova, Andrea ;
Revil, Cedric ;
Jones, Alison .
JOURNAL OF CLINICAL ONCOLOGY, 2009, 27 (33) :5529-5537
[4]   Causal inference through potential outcomes and principal stratification: Application to studies with "censoring" due to death - Comments and rejoiners [J].
Korn, Edward L. ;
Rosenbaum, Paul R. ;
Fienberg, Stephen E. ;
Rubin, Donald B. .
STATISTICAL SCIENCE, 2006, 21 (03) :310-321
[5]  
Korn EL, 1998, STAT SCI, V13, P209
[6]   Phase II Randomized Comparison of Topotecan Plus Cyclophosphamide Versus Topotecan Alone in Children With Recurrent or Refractory Neuroblastoma: A Children's Oncology Group Study [J].
London, Wendy B. ;
Frantz, Christopher N. ;
Campbell, Laura A. ;
Seeger, Robert C. ;
Brumback, Babette A. ;
Cohn, Susan L. ;
Matthay, Katherine K. ;
Castleberry, Robert P. ;
Diller, Lisa .
JOURNAL OF CLINICAL ONCOLOGY, 2010, 28 (24) :3808-3815
[7]   Efficacy of everolimus in advanced renal cell carcinoma:: a double-blind, randomised, placebo-controlled phase III trial [J].
Motzer, Robert J. ;
Escudier, Bernard ;
Oudard, Stephane ;
Hutson, Thomas E. ;
Porta, Camillo ;
Bracarda, Sergio ;
Gruenwald, Viktor ;
Thompson, John A. ;
Figlin, Robert A. ;
Hollaender, Norbert ;
Urbanowitz, Gladys ;
Berg, William J. ;
Kay, Andrea ;
Lebwohl, David ;
Ravaud, Alain .
LANCET, 2008, 372 (9637) :449-456
[8]  
National Institute for Health and Clinical Excellence, 179 NAT I HLTH CLIN
[9]  
ROBBINS JM, 1991, COMMUN STAT-THEOR M, V20, P2609
[10]   EPIC:: Phase III trial of cetuximab plus irinotecan after fluoropyrimidine and oxaliplatin failure in patients with metastatic colorectal cancer [J].
Sobrero, Alberto F. ;
Maurel, Joan ;
Fehrenbacher, Louis ;
Scheithauer, Werner ;
Abubakr, Yousif A. ;
Lutz, Manfred P. ;
Vega-Villegas, M. Eugenia ;
Eng, Cathy ;
Steinhauer, Ernst U. ;
Prausova, Jana ;
Lenz, Heinz-Josef ;
Borg, Christophe ;
Middleton, Gary ;
Kroening, Hendrik ;
Luppi, Gabriele ;
Kisker, Oliver ;
Zubel, Angela ;
Langer, Christiane ;
Kopit, Justin ;
Burris, Howard A., III .
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (14) :2311-2319