Chemoenzymatic synthesis of (+)-(4E,15E)-docosa-4,15-dien-1-yn-3-ol, a component of the marine sponge Cribrochalina vasculum

被引：8

作者：

Ohtani, T

Kikuchi, K

Kamezawa, M

Hamatani, H

Tachibana, H

Totani, T

Naoshima, Y

机构：

[1] OKAYAMA UNIV,FAC SCI,DEPT BIOCHEM,OKAYAMA 700,JAPAN

[2] KONAN CHEM IND CO LTD,TAKATSUKI,OSAKA 569,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1996年 / 10期

关键词：

PROPARGYLIC ALCOHOLS; ACETYLENIC ALCOHOLS;

D O I：

10.1039/p19960000961

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An acetylenic alcohol, (+)-(4E, 15E)-docosa-4, 15-dien-1-yn-3-ol 1, isolated from the marine sponge Cribrochalina vasculum, was synthesized in highly enantiomerically pure form by lipase-catalysed transesterification with Novozym 435 (Candida antarctica).

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页码：961 / 962

页数：2

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