PILATUS:: a two-dimensional X-ray detector for macromolecular crystallography

被引:107
作者
Eikenberry, EF
Brönnimann, C
Hülsen, G
Toyokawa, H
Horisberger, R
Schmitt, B
Schulze-Briese, C
Tomizaki, T
机构
[1] Paul Scherrer Inst, SLS, CH-5232 Villigen, Switzerland
[2] Japan Synchrotron Radiat Res Inst, Mikazuki, Hyogo 6795198, Japan
关键词
X-ray crystallography; single-photon counting; bump-bonding; threshold trimming;
D O I
10.1016/S0168-9002(02)02044-2
中图分类号
TH7 [仪器、仪表];
学科分类号
0804 ; 080401 ; 081102 ;
摘要
A large quantum-limited area X-ray detector for protein crystallography is under development at the Swiss Light Source. The final detector will be 2k x 2k pixels covering 40 x 40 cm(2). A three-module prototype with 1120 x 157 pixels covering an active area of 24.3 x 3.4 cm(2) has been tested. X-rays above 6 keV with peak count rates exceeding 5 x 10(5) X-ray/pixel/s could be detected in single photon counting mode. Statistics of module production and results of threshold trimming are presented. To demonstrate the potential of this new detector, protein crystal data were collected at beamline 6S of the SLS. (C) 2002 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:260 / 266
页数:7
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