Chemical synthesis at solid interfaces. On the use of conducting polythiophenes equipped of adequate linkers allowing a facile and highly selective cathodic S-N bond scission with a fully regenerating resin process.

被引：24

作者：

Pilard, JF ^{[1
]}

Marchand, G ^{[1
]}

Simonet, J ^{[1
]}

机构：

[1] Univ Rennes 1, UMR 6510, Lab Electrochim Mol & Macromol, F-35042 Rennes, France

来源：

TETRAHEDRON | 1998年 / 54卷 / 32期

关键词：

solid interface synthesis; cathodic cleavage; nitrogen-sulfur bonds; combinatorial chemistry;

D O I：

10.1016/S0040-4020(98)00580-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Electrogenerated polythiophenes were evaluated as;Merrifield-like resins for the anchoring of amine functions together with deprotection processes. Suitable linkers were terminated with a fully regenerable aromatic sulfonamide moiety. The S-N bond was cleaved to liberate the amine with high selectivity under very mild conditions by cathodic means with amine liberation. Moreover a facile recycling process of the resin allows the further grafting of various amine functions. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：9401 / 9414

页数：14

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