Induction of apoptosis by Chlamydia psittaci and Chlamydia trachomatis infection in tissue culture cells

被引：32

作者：

Gibellini, D ^{[1
]}

Panaya, R ^{[1
]}

Rumpianesi, F ^{[1
]}

机构：

[1] Univ Bologna, St Orsola Gen Hosp, Dept Clin & Expt Med, Microbiol Sect, I-40138 Bologna, Italy

来源：

ZENTRALBLATT FUR BAKTERIOLOGIE-INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY VIROLOGY PARASITOLOGY AND INFECTIOUS DISEASES | 1998年 / 288卷 / 01期

关键词：

D O I：

10.1016/S0934-8840(98)80095-9

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The role of programmed cell death (apoptosis) in LLC-MK2 cells infected with Chlamydia trachomatis LGV2 serotype and Chlamydia psittaci 6BC strain was investigated using flow cytometry and TUNEL procedures. The number of apoptotic cells was significantly higher at 72 and 96 hours post infection in the Chlamydia infected cell cultures in comparison with mock-infected cells. We postulate the apoptotic process to be a mechanism induced by C. trachomatis and C. psittaci infection in LLC-MK2 cells.

引用

页码：35 / 43

页数：9

共 17 条

[1]

BOSE SK, 1979, INFECT IMMUN, V34, P154

[2] ENHANCED CELL-SURVIVAL AND TUMORIGENESIS [J].

CORY, S ;

STRASSER, A ;

JACKS, T ;

CORCORAN, LM ;

METZ, T ;

HARRIS, AW ;

ADAMS, JM .

COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1994, 59 :365-375

[3]

Darzynkiewicz Z, 1993, CELL CYCLE PRACTICAL, P45

[4] DIVISION OF SINGLE HOST-CELLS AFTER INFECTION WITH CHLAMYDIAE [J].

HOROSCHAK, KD ;

MOULDER, JW .

INFECTION AND IMMUNITY, 1978, 19 (01) :281-286

[5] Infection by Mycobacterium tuberculosis promotes human alveolar macrophage apoptosis [J].

Keane, J ;

BalcewiczSablinska, MK ;

Remold, HG ;

Chupp, GL ;

Meek, BB ;

Fenton, MJ ;

Kornfeld, H .

INFECTION AND IMMUNITY, 1997, 65 (01) :298-304

[6] APOPTOSIS - BASIC BIOLOGICAL PHENOMENON WITH WIDE-RANGING IMPLICATIONS IN TISSUE KINETICS [J].

KERR, JFR ;

WYLLIE, AH ;

CURRIE, AR .

BRITISH JOURNAL OF CANCER, 1972, 26 (04) :239-+

[7] INTERACTION OF CHLAMYDIAE AND HOST-CELLS INVITRO [J].

MOULDER, JW .

MICROBIOLOGICAL REVIEWS, 1991, 55 (01) :143-190

[8] A RAPID AND SIMPLE METHOD FOR MEASURING THYMOCYTE APOPTOSIS BY PROPIDIUM IODIDE STAINING AND FLOW-CYTOMETRY [J].

NICOLETTI, I ;

MIGLIORATI, G ;

PAGLIACCI, MC ;

GRIGNANI, F ;

RICCARDI, C .

JOURNAL OF IMMUNOLOGICAL METHODS, 1991, 139 (02) :271-279

[9]

RAZVI ES, 1995, ADV VIRUS RES, V45, P1, DOI 10.1016/S0065-3527(08)60057-3

[10] INDUCTION OF PROGRAMMED CELL-DEATH (APOPTOSIS) BY INFLUENZA-VIRUS INFECTION IN TISSUE-CULTURE CELLS [J].

TAKIZAWA, T ;

MATSUKAWA, S ;

HIGUCHI, Y ;

NAKAMURA, S ;

NAKANISHI, Y ;

FUKUDA, R .

JOURNAL OF GENERAL VIROLOGY, 1993, 74 :2347-2355

← 1 2 →