Intoxications Amenable to Extracorporeal Removal

被引:6
作者
Winchester, James F. [1 ]
Harbord, Nikolas B. [1 ]
机构
[1] Beth Israel Deaconess Med Ctr, Div Nephrol & Hypertens, New York, NY 10003 USA
关键词
Toxins; Dialysis; Hemoperfusion; Pharmacokinetics; Toxokinetics; HEMOPERFUSION; HEMODIALYSIS; ELIMINATION; FOMEPIZOLE; DIALYSIS; EFFICACY; POISONS; FAILURE; PATIENT; KIDNEY;
D O I
10.1053/j.ackd.2010.10.007
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Extracorporeal removal of drugs was first attempted in 1913, by John Jacob Abel. Previously known to be a rarity, dialysis and to a lesser extent hemoperfusion have now become obvious tools for nephrologists in treating life-threatening cases of poisoning. Moreover, for dialysis patients, dialysis along with chelation therapy for removal of aluminum, once known to be common in the United States, is resurging in some countries. This article will discuss the principles of drug removal, the indications for dialysis, and give a brief outline of poisons amenable to dialysis. (C) 2011 by the National Kidney Foundation, Inc. All rights reserved.
引用
收藏
页码:167 / 171
页数:5
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