Antiamoebic activity of Piper longum fruits against Entamoeba histolytica in vitro and in vivo

被引：80

作者：

Ghoshal, S ^{[1
]}

Prasad, BNK ^{[1
]}

Lakshmi, V ^{[1
]}

机构：

[1] CENT DRUG RES INST, DIV MED CHEM, LUCKNOW 226001, UTTAR PRADESH, INDIA

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1996年 / 50卷 / 03期

关键词：

antiamoebic; Entamoeba histolytica; Piper longum; piperine;

D O I：

10.1016/0378-8741(96)01382-7

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The fruits of Piper longum used in traditional remedies against intestinal distress have been tested for their efficacy against experimental caecal amoebiasis of rats. The ethanolic extract, hexane fraction, n-butanol soluble fraction exerted in vitro amoebicidal action at 1000 mu g/ml and the chloroform fraction at 500 mu g/ml. The ethanolic extract and piperine, a pure compound, from this plant material cured 90% and 40% of rats with caecal amoebiasis, respectively.

引用

页码：167 / 170

页数：4

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