HEMATOLOGY Curing CML with imatinib-a dream come true?

被引:23
作者
Deininger, Michael [1 ]
机构
[1] Univ Utah, Div Hematol & Hematol Malignancies, Huntsman Canc Inst, Salt Lake City, UT 84112 USA
关键词
CHRONIC MYELOID-LEUKEMIA; COMPLETE MOLECULAR REMISSION; DISCONTINUATION;
D O I
10.1038/nrclinonc.2011.17
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Imatinib was discontinued in patients with chronic myeloid leukemia (cMl) who gained a complete molecular response (cMR). of those patients with at least 12 months follow-up, 61% experienced recurrence, all of whom responded to rechallenge. The remaining patients maintained cMR, suggesting that imatinib may 'cure' a small proportion of patients with cMl. © 2011 Macmillan Publishers Limited. All rights reserved.
引用
收藏
页码:127 / 128
页数:2
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