Polymeric Scaffolds for Regenerative Medicine

被引：97

作者：

Kim, Moon Suk ^{[1
]}

Kim, Jae Ho ^{[1
]}

Min, Byoung Hyun ^{[1
,2
]}

Chun, Heung Jae ^{[3
]}

Han, Dong Keun ^{[4
]}

Lee, Hai Bang ^{[1
]}

机构：

[1] Ajou Univ, Dept Mol Sci & Technol, Suwon 443749, South Korea

[2] Ajou Univ, Dept Orthoped Surg, Suwon 443749, South Korea

[3] Catholic Univ, Dept Biomed Sci, Seoul 137701, South Korea

[4] Korea Inst Sci & Technol, Seoul 130650, South Korea

来源：

POLYMER REVIEWS | 2011年 / 51卷 / 01期

关键词：

polymeric scaffold; biomaterials; tissue engineering; regenerative medicine; SMALL-INTESTINAL SUBMUCOSA; MESENCHYMAL STEM-CELLS; VIVO OSTEOGENIC DIFFERENTIATION; PCL DIBLOCK COPOLYMER; IN-VIVO; EXTRACELLULAR-MATRIX; POLY(ETHYLENE GLYCOL); CROSS-LINKING; BLOCK-COPOLYMERS; HYALURONIC-ACID;

D O I：

10.1080/15583724.2010.537800

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 [高分子化学与物理];

摘要：

Regenerative medicine, one of the most exciting and dynamic life science fields, is an emerging biomedical technology for assisting and accelerating the regeneration and repair of lost or damaged organs or body parts. Modern regenerative medicine is increasingly using three-dimensional structured scaffolds because they represent a wide range of morphological and geometric in vivo possibilities that can be tailored for each specific regenerative medicine application. This review focuses on polymeric scaffolds, a highly promising regenerative medicine strategy, summarizing some important issues related to various natural and synthetic scaffolding biomaterials, techniques on the design and fabrication of three-dimensional polymeric scaffolds to mimic the properties of the extracellular matrix, and clinical applications of polymeric scaffolds for tissue regeneration.

引用

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页数：30

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