Epidemiology and aetiology of basal cell carcinoma

被引:171
作者
Roewert-Huber, J. [1 ]
Lange-Asschenfeldt, B.
Stockfleth, E.
Kerl, H.
机构
[1] Univ Hosp Berlin, Skin Canc Ctr Charite, Dept Dermatol Venereol & Allergy, Berlin, Germany
[2] Graz Univ, Dept Dermatol, Graz, Austria
关键词
aetiology; basal cell carcinoma; epidemiology;
D O I
10.1111/j.1365-2133.2007.08273.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Basal cell carcinoma (BCC) is a malignant epithelial neoplasm of the skin preferentially affecting male caucasians and is rarely observed in patients with more intense skin pigmentation. A characteristic feature of BCCs are their extremely low risk to metastasize. Epidemiological data indicate that the overall incidence is increasing worldwide significantly by about 3-10% per annum.(1-3) Based on the increasing incidence of this usually not life-threatening tumour BCC appears to develop into a growing public health problem. This review elucidates the risk factors for the development and for the progression of BCC leading to an improved understanding of this tumour.
引用
收藏
页码:47 / 51
页数:5
相关论文
共 67 条
[1]   Chemokines in pathology and medicine [J].
Baggiolini, M .
JOURNAL OF INTERNAL MEDICINE, 2001, 250 (02) :91-104
[2]   Basal cell carcinoma in young women: An evaluation of the association of tanning bed use and smoking [J].
Boyd, AS ;
Shyr, Y ;
King, LE .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2002, 46 (05) :706-709
[3]  
Brash DE, 1996, JOURNAL OF INVESTIGATIVE DERMATOLOGY SYMPOSIUM PROCEEDINGS, VOL 1, NO 2, APRIL 1996, P136
[4]   CULTURE OF BASAL-CELL CARCINOMA [J].
BRYSK, MM ;
SANTSCHI, CH ;
BELL, T ;
WAGNER, RF ;
TYRING, SK ;
RAJARAMAN, S .
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 1992, 98 (01) :45-49
[5]   CODON-12 HARVEY-RAS MUTATIONS ARE RARE EVENTS IN NONMELANOMA HUMAN SKIN-CANCER [J].
CAMPBELL, C ;
QUINN, AG ;
REES, JL .
BRITISH JOURNAL OF DERMATOLOGY, 1993, 128 (02) :111-114
[6]   CXC chemokine receptor CXCR4 expression enhances tumorigenesis and angiogenesis of basal cell carcinoma [J].
Chen, GS ;
Yu, HS ;
Lan, CCE ;
Chow, KC ;
Lin, TY ;
Kok, LF ;
Lu, MP ;
Liu, CH ;
Wu, MT .
BRITISH JOURNAL OF DERMATOLOGY, 2006, 154 (05) :910-918
[7]  
Corona R, 2001, ARCH DERMATOL, V137, P1162
[8]   Relation between smoking and skin cancer [J].
De Hertog, SAE ;
Wensveen, CAH ;
Bastiaens, MT ;
Kielich, CJ ;
Berkhout, MJP ;
Westendorp, RGJ ;
Vermeer, BJ ;
Bavinck, JNB .
JOURNAL OF CLINICAL ONCOLOGY, 2001, 19 (01) :231-238
[9]  
Dicker Tony, 2002, Australas J Dermatol, V43, P241, DOI 10.1046/j.1440-0960.2002.00609.x
[10]   SOLAR DOSIMETRY OF THE FACE - RELATIONSHIP OF NATURAL ULTRAVIOLET-RADIATION EXPOSURE TO BASAL-CELL CARCINOMA LOCALIZATION [J].
DIFFEY, BL ;
TATE, TJ ;
DAVIS, A .
PHYSICS IN MEDICINE AND BIOLOGY, 1979, 24 (05) :931-939