Highly enantioselective Cr(salen)-catalyzed reaction of 2-(trimethylsilyloxy)furan and aldehydes. Effect of alcohol on enantioselectivity

被引:44
作者
Onitsuka, S
Matsuoka, Y
Irie, R
Katsuki, T [1 ]
机构
[1] Kyushu Univ 33, Fac Sci, Dept Chem, Higashi Ku, Fukuoka 8128581, Japan
[2] Japan Sci & Technol, CREST, JST, Higashi Ku, Fukuoka 8128581, Japan
关键词
D O I
10.1246/cl.2003.974
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Reactions of 2-(trimethylsilyloxy)furan I and aldehydes catalyzed by a chiral cationic Cr(salen) complex proceeded with remarkably improved enantioselectivity, when a secondary alcohol was added. The role of the alcohol is acceleration of the conversion of an intermediary I-aldehyde adduct into the final product.
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页码:974 / 975
页数:2
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