Impact of Comorbidities on ischemic stroke outcomes in women

被引：41

作者：

Bushnell, Cheryl D. ^{[1
]}

Lee, Jeanne

Duncan, Pamela W. ^{[2
]}

Newby, L. Kristin ^{[3
]}

Goldstein, Larry B. ^{[1
]}

机构：

[1] Duke Univ, Med Ctr, Ctr Cerebrovasc Dis, Dept Med,Div Neurol, Durham, NC USA

[2] Duke Univ, Med Ctr, Dept Community & Family Med, Div Phys Therapy, Durham, NC USA

[3] Duke Clin Res Inst, Dept Med, Div Cardiol, Durham, NC USA

来源：

STROKE | 2008年 / 39卷 / 07期

关键词：

acute stroke; outcome stroke; recovery women and minorities; comorbidities;

D O I：

10.1161/STROKEAHA.107.509281

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background and Purpose - We assessed the association of prestroke comorbidities with long-term stroke outcomes among women with ischemic stroke. Methods - Prestroke comorbid conditions in 133 women admitted with acute ischemic stroke were scored with the Charlson Index (CI). We assessed whether the CI and other specific conditions were associated with modified Rankin Score (mRS) at 90 days or more poststroke. Results - After adjustment for initial NIHSS and age, higher CI was the sole factor independently associated with poorer 90 day mRS scores. When CI was excluded, coronary disease and diabetes were independently associated with poorer outcome. Conclusion - The extent of comorbidities as assessed by the CI is independently associated with 90-day mRS among women with ischemic stroke, but the individual comorbidities of CHD and DM were each associated with functional outcome.

引用

页码：2138 / 2140

页数：3

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