Molecular genetic approaches to understanding the actin cytoskeleton

被引:38
作者
Sutherland, JD [1 ]
Witke, W [1 ]
机构
[1] European Mol Biol Lab, Mouse Biol Programme, I-00016 Monterotondo, Italy
关键词
D O I
10.1016/S0955-0674(99)80018-0
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
New tools in molecular genetics, such as genetic interaction screens and conditional gene targeting, have advanced the study of actin dynamics in a number of model systems. Yeast, Dictyostelium, Caenorhabditis elegans, Drosophila, and mice have contributed much in recent years to a better understanding of both the numerous functions and modes of regulation of the actin cytoskeleton.
引用
收藏
页码:142 / 151
页数:10
相关论文
共 107 条
  • [1] Dictyostelium IQGAP-related protein specifically involved in the completion of cytokinesis
    Adachi, H
    Takahashi, Y
    Hasebe, T
    Shirouzu, M
    Yokoyama, S
    Sutoh, K
    [J]. JOURNAL OF CELL BIOLOGY, 1997, 137 (04) : 891 - 898
  • [2] Vinculin gene is non-essential in Drosophila melanogaster
    Alatortsev, VE
    Kramerova, IA
    Frolov, MV
    Lavrov, SA
    Westphal, ED
    [J]. FEBS LETTERS, 1997, 413 (02) : 197 - 201
  • [3] Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways
    Axelrod, JD
    Miller, JR
    Shulman, JM
    Moon, RT
    Perrimon, N
    [J]. GENES & DEVELOPMENT, 1998, 12 (16) : 2610 - 2622
  • [4] The rho GTPase and a putative RhoGEF mediate a signaling pathway for the cell shape changes in Drosophila gastrulation
    Barrett, K
    Leptin, M
    Settleman, J
    [J]. CELL, 1997, 91 (07) : 905 - 915
  • [5] SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development
    Bear, JE
    Rawls, JF
    Saxe, CL
    [J]. JOURNAL OF CELL BIOLOGY, 1998, 142 (05) : 1325 - 1335
  • [6] Bello B, 1998, DEVELOPMENT, V125, P2193
  • [7] Bypass of lethality with mosaic mice generated by Cre-loxP-mediated recombination
    Betz, UAK
    Vosshenrich, CAJ
    Rajewsky, K
    Muller, W
    [J]. CURRENT BIOLOGY, 1996, 6 (10) : 1307 - 1316
  • [8] Doxycycline-induced transgene expression during Drosophila development and aging
    Bieschke, ET
    Wheeler, JC
    Tower, J
    [J]. MOLECULAR AND GENERAL GENETICS, 1998, 258 (06): : 571 - 579
  • [9] Dishevelled activates JNK and discriminates between JNK pathways in planar polarity and wingless signaling
    Boutros, M
    Paricio, N
    Strutt, DI
    Mlodzik, M
    [J]. CELL, 1998, 94 (01) : 109 - 118
  • [10] GFP IN DROSOPHILA
    BRAND, A
    [J]. TRENDS IN GENETICS, 1995, 11 (08) : 324 - 325