Evaluation of a rapid PCR assay for diagnosis of meningococcal meningitis

被引：36

作者：

Richardson, DC ^{[1
]}

Louie, L ^{[1
]}

Louie, M ^{[1
]}

Simor, AE ^{[1
]}

机构：

[1] Univ Toronto, Sunnybrook & Womens Coll, Hlth Sci Ctr, Dept Microbiol, Toronto, ON M4N 3M5, Canada

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2003年 / 41卷 / 08期

关键词：

D O I：

10.1128/JCM.41.8.3851-3853.2003

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We compared the results of Gram staining and culture of cerebrospinal fluid to results obtained with a rapid PCR assay for the diagnosis of meningococcal meningitis in 281 cases of suspected bacterial meningitis. PCR had a sensitivity of 97% compared to a sensitivity of 55% for culture, and the PCR specificity was 99.6%. PCR results were available within 2 h of the start of the assay.

引用

页码：3851 / 3853

页数：3

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