Will radioiodine be useful in treatment of breast cancer?

被引:22
作者
Daniels, GH [1 ]
Haber, DA
机构
[1] Harvard Univ, Sch Med, Dept Med, Thyroid Unit, Boston, MA 02115 USA
[2] Massachusetts Gen Hosp, Ctr Canc, Boston, MA 02115 USA
关键词
D O I
10.1038/78604
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Expression of a sodium iodide transporter by the thyroid gland causes iodide accumulation, and radioactive iodide is an effective treatment for thyroid cancer. The identification of a similar transporter in mammary tissue indicates that this approach might also be used to treat breast cancer (pages 871-878).
引用
收藏
页码:859 / 860
页数:2
相关论文
共 8 条
[1]  
[Anonymous], 2000, WERNER INGBARS THYRO
[2]   Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease [J].
Cobleigh, MA ;
Vogel, CL ;
Tripathy, D ;
Robert, NJ ;
Scholl, S ;
Fehrenbacher, L ;
Wolter, JM ;
Paton, V ;
Shak, S ;
Lieberman, G ;
Slamon, DJ .
JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (09) :2639-2648
[3]   Cloning and characterization of the thyroid iodide transporter [J].
Dai, G ;
Levy, O ;
Carrasco, N .
NATURE, 1996, 379 (6564) :458-460
[4]  
Mandell RB, 1999, CANCER RES, V59, P661
[5]  
Marine D, 1915, J PHARMACOL EXP THER, V7, P557
[6]   RELATION BETWEEN EFFECTIVE RADIATION-DOSE AND OUTCOME OF RADIOIODINE THERAPY FOR THYROID-CANCER [J].
MAXON, HR ;
THOMAS, SR ;
HERTZBERG, VS ;
KEREIAKES, JG ;
CHEN, IW ;
SPERLING, MI ;
SAENGER, EL .
NEW ENGLAND JOURNAL OF MEDICINE, 1983, 309 (16) :937-941
[7]   Radioiodine and the treatment of hyperthyroidism: The early history [J].
Sawin, CT ;
Becker, DV .
THYROID, 1997, 7 (02) :163-176
[8]   The mammary gland iodide transporter is expressed during lactation and in breast cancer [J].
Tazebay, UH ;
Wapnir, IL ;
Levy, O ;
Dohan, O ;
Zuckier, LS ;
Zhao, QH ;
Deng, HF ;
Amenta, PS ;
Fineberg, S ;
Pestell, RG ;
Carrasco, N .
NATURE MEDICINE, 2000, 6 (08) :871-878