Neurobiology of anorexia nervosa: Clinical implications of alterations of the function of serotonin and other neuronal systems

被引：71

作者：

Kaye, WH ^{[1
]}

Frank, GK

Bailer, UF

Henry, SE

机构：

[1] Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA 15213 USA

[2] Univ Pittsburgh, Eating Disorders Res Dept, Pittsburgh, PA USA

来源：

INTERNATIONAL JOURNAL OF EATING DISORDERS | 2005年 / 37卷

关键词：

D O I：

10.1002/eat.20109

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Recent evidence suggests that genetic and neurobiologically mediated mechanisms contribute to the etiology of anorexia nervosa (AN). Serotonin neuronal systems, in particular, may create vulnerabilities related to pathological feeding, anxiety and obsessions, and extremes of impulse control, that make individuals susceptible to developing an eating disorder, perhaps in combination with environmental stressors. © 2005 by Wiley Periodicals, Inc.

引用

页码：S15 / S19

页数：5

共 29 条

[1] A database of [18F]-altanserin binding to 5-HT2A receptors in normal volunteers:: normative data and relationship to physiological and demographic variables [J].

Adams, KH ;

Pinborg, LH ;

Svarer, C ;

Hasselbalch, SG ;

Holm, S ;

Haugbol, S ;

Madsen, K ;

Frokjær, V ;

Martiny, L ;

Paulson, OB ;

Knudsen, GM .

NEUROIMAGE, 2004, 21 (03) :1105-1113

[2] Does fluoxetine augment the inpatient treatment of anorexia nervosa? [J].

Attia, E ;

Haiman, C ;

Walsh, T ;

Flater, SR .

AMERICAN JOURNAL OF PSYCHIATRY, 1998, 155 (04) :548-551

[3]

Audenaert K, 2003, J NUCL MED, V44, P163

[4] Altered 5-HT2A receptor binding after recovery from bulimia-type anorexia nervosa:: Relationships to harm avoidance and drive for thinness [J].

Bailer, UF ;

Price, JC ;

Meltzer, CC ;

Mathis, CA ;

Frank, GK ;

Weissfeld, L ;

McConaha, CW ;

Henry, SE ;

Brooks-Achenbach, S ;

Barbarich, NC ;

Kaye, WH .

NEUROPSYCHOPHARMACOLOGY, 2004, 29 (06) :1143-1155

[5] Possible serotonergic mechanisms underlying the antidepressant and anti-obsessive-compulsive disorder responses [J].

Blier, P ;

de Montigny, C .

BIOLOGICAL PSYCHIATRY, 1998, 44 (05) :313-323

[6]

BREWERTON TD, 1990, SEROTONIN MAJOR PSYC, P155

[7]

Charney DS, 1996, CRIT REV NEUROBIOL, V10, P419

[8] A PSYCHOBIOLOGICAL MODEL OF TEMPERAMENT AND CHARACTER [J].

CLONINGER, CR ;

SVRAKIC, DM ;

PRZYBECK, TR .

ARCHIVES OF GENERAL PSYCHIATRY, 1993, 50 (12) :975-990

[9]

COOPER J, 1996, BIOCH BASIS NEUROPHA

[10]

Ferguson CP, 1999, INT J EAT DISORDER, V25, P11, DOI 10.1002/(SICI)1098-108X(199901)25:1<11::AID-EAT2>3.0.CO

← 1 2 3 →