Fructans interact strongly with model membranes

被引:67
作者
Demel, RA
Dorrepaal, E
Ebskamp, MJM
Smeekens, JCM
de Kruijff, B
机构
[1] Univ Utrecht, Ctr Biomembranes & Lipid Enzymol, Dept Membrane Biochem, NL-3584 CH Utrecht, Netherlands
[2] Univ Utrecht, Biomembrane Inst, Dept Mol Cell Biol, NL-3584 CH Utrecht, Netherlands
来源
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES | 1998年 / 1375卷 / 1-2期
关键词
monomolecular layer; carbohydrate; fructan; desiccation; phase transition; phospholipid;
D O I
10.1016/S0005-2736(98)00138-2
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Bacterial fructans with a high degree of polymerisation cause a very large increase in surface pressure of lipid monolayers at the air-water interface with a broad range of lipids, including phosphatidylethanolamine and several types of phosphatidylcholines. The surface active effect of fructans contrasts strongly with the maximal effects observed for trehalose, sucrose and glucose under comparable conditions (20 and 0.6 mN/m for fructans and the other sugars, respectively). The results demonstrate a profound and specific membrane interaction of the fructans which is probably very different from the effect of the smaller carbohydrates. The fructan concentrations used in this study are within the physiological range observed in fructan-accumulating plants. The suggested water-stress protective effect of fructans may be induced by membrane-fructan interaction which prevent lipid condensation and phase transitions to take place. (C) 1998 Elsevier Science B.V. All rights reserved.
引用
收藏
页码:36 / 42
页数:7
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