Animal models for the study of arterial hypertension

被引：108

作者：

Dornas, Waleska C. ^{[2
]}

Silva, Marcelo E. ^{[1
]}

机构：

[1] Ouro Preto Univ, Sch Nutr, Dept Foods, Belo Horizonte, MG, Brazil

[2] Ouro Preto Univ, Res Biol Sci NUPEB, Belo Horizonte, MG, Brazil

来源：

JOURNAL OF BIOSCIENCES | 2011年 / 36卷 / 04期

关键词：

Blood pressure; cardiovascular disease; experimental models; hypertension; NITRIC-OXIDE SYNTHESIS; SYMPATHETIC-NERVOUS-SYSTEM; BLOOD-PRESSURE; CHRONIC BLOCKADE; BARORECEPTOR DENERVATION; CARDIAC-HYPERTROPHY; SALT SENSITIVITY; HIGH-FAT; STRESS; RATS;

D O I：

10.1007/s12038-011-9097-y

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Hypertension is one of the leading causes of disability or death due to stroke, heart attack and kidney failure. Because the etiology of essential hypertension is not known and may be multifactorial, the use of experimental animal models has provided valuable information regarding many aspects of the disease, which include etiology, pathophysiology, complications and treatment. The models of hypertension are various, and in this review, we provide a brief overview of the most widely used animal models, their features and their importance.

引用

页码：731 / 737

页数：7

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