Cholesterol, hedgehog and embryogenesis

被引：26

作者：

Herz, J

Willnow, TE

Farese, RV

机构：

[1] MAX DELBRUCK CTR MOL MED,D-13125 BERLIN,GERMANY

[2] UNIV CALIF SAN FRANCISCO,GLADSTONE INST CARDIOVASC DIS,SAN FRANCISCO,CA 94141

[3] UNIV CALIF SAN FRANCISCO,DEPT MED,SAN FRANCISCO,CA 94141

来源：

NATURE GENETICS | 1997年 / 15卷 / 02期

关键词：

D O I：

10.1038/ng0297-123

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：123 / 124

页数：2

共 10 条

[1] Identification of Sonic hedgehog as a candidate gene responsible for holoprosencephaly [J].

Belloni, E ;

Muenke, M ;

Roessler, E ;

Traverso, G ;

SiegelBartelt, J ;

Frumkin, A ;

Mitchell, HF ;

DonisKeller, H ;

Helms, C ;

Hing, AV ;

Heng, HHQ ;

Koop, B ;

Martindale, D ;

Rommens, JM ;

Tsui, LC ;

Scherer, SW .

NATURE GENETICS, 1996, 14 (03) :353-356

[2] Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function [J].

Chiang, C ;

Ying, LTT ;

Lee, E ;

Young, KE ;

Corden, JL ;

Westphal, H ;

Beachy, PA .

NATURE, 1996, 383 (6599) :407-413

[3]

Farese RV, 1996, J LIPID RES, V37, P347

[4] KNOCKOUT OF THE MOUSE APOLIPOPROTEIN-B GENE RESULTS IN EMBRYONIC LETHALITY IN HOMOZYGOTES AND PROTECTION AGAINST DIET-INDUCED HYPERCHOLESTEROLEMIA IN HETEROZYGOTES [J].

FARESE, RV ;

RULAND, SL ;

FLYNN, LM ;

STOKOWSKI, RP ;

YOUNG, SG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (05) :1774-1778

[5] TARGETED MODIFICATION OF THE APOLIPOPROTEIN-B GENE RESULTS IN HYPOBETALIPOPROTEINEMIA AND DEVELOPMENTAL ABNORMALITIES IN MICE [J].

HOMANICS, GE ;

SMITH, TJ ;

ZHANG, SH ;

LEE, D ;

YOUNG, SG ;

MAEDA, N .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (06) :2389-2393

[6] APO-B GENE KNOCKOUT IN MICE RESULTS IN EMBRYONIC LETHALITY IN HOMOZYGOTES AND NEURAL-TUBE DEFECTS, MALE-INFERTILITY, AND REDUCED HDL CHOLESTEROL ESTER AND APO-A-I TRANSPORT RATES IN HETEROZYGOTES [J].

HUANG, LS ;

VOYIAZIAKIS, E ;

MARKENSON, DF ;

SOKOL, KA ;

HAYEK, T ;

BRESLOW, JL .

JOURNAL OF CLINICAL INVESTIGATION, 1995, 96 (05) :2152-2161

[7] Cholesterol modification of hedgehog signaling proteins in animal development [J].

Porter, JA ;

Young, KE ;

Beachy, PA .

SCIENCE, 1996, 274 (5285) :255-259

[8] Mutations in the human Sonic hedgehog gene cause holoprosencephaly [J].

Roessler, E ;

Belloni, E ;

Gaudenz, K ;

Jay, P ;

Berta, P ;

Scherer, SW ;

Tsui, LC ;

Muenke, M .

NATURE GENETICS, 1996, 14 (03) :357-360

[9]

Salen G, 1996, J LIPID RES, V37, P1169

[10] Defective forebrain development in mice lacking gp330/megalin [J].

Willnow, TE ;

Hilpert, J ;

Armstrong, SA ;

Rohlmann, A ;

Hammer, RE ;

Burns, DK ;

Herz, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (16) :8460-8464

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