Evaluation of a new Plasmodium lactate dehydrogenase assay (OptiMAL-IT®) for the detection of malaria

被引：36

作者：

Pattanasin, S. ^{[1
]}

Proux, S. ^{[1
]}

Chompasuk, D. ^{[1
]}

Luwiradaj, K. ^{[1
]}

Jacquier, P. ^{[4
]}

Looareesuwan, S. ^{[2
]}

Nosten, F. ^{[1
,2
,3
]}

机构：

[1] SMRU, St Louis, MO 63110 USA

[2] Mahidol Univ, Fac Trop Med, Bangkok, Thailand

[3] John Radcliffe Hosp, Ctr Trop Med, Oxford, England

[4] DiaMed, Basel, Switzerland

来源：

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE | 2003年 / 97卷 / 06期

基金：

英国惠康基金;

关键词：

malaria; Plasmodium falciparum; Plasmodium lactate dehydrogenase; histidine-rich protein II;

D O I：

10.1016/S0035-9203(03)80100-1

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The new OptiMAL-IT (R) rapid diagnostic test for malaria was evaluated in 271 patients in Thailand with uncomplicated malaria between June and July 2002. The sensitivity and specificity for the diagnosis of Plasmodium falciparum parasites were 88% and 92%, respectively. For species other than P. falciparum, the sensitivity was 65% and specificity was 99%. The performance of the new test decreased markedly at low levels of parasitaemia.

引用

收藏

页码：672 / 674

页数：3

相关论文

共 13 条

[1] Short report:: Failure of the OptiMAL® rapid malaria test as a tool for the detection of asymptomatic malaria in an area of Thailand endemic for Plasmodium falciparum and P-vivax [J].

Coleman, RE ;

Maneechai, N ;

Ponlawat, A ;

Kumpitak, C ;

Rachapaew, N ;

Miller, RS ;

Sattabongkot, J .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2002, 67 (06) :563-565

[2] Performance of the OptiMAL® assay for detection and identification of malaria infections in asymptomatic residents of Irian Jaya, Indonesia [J].

Fryauff, DJ ;

Purnomo ;

Sutamihardja, MA ;

Elyazar, IRS ;

Susanti, I ;

Krisin ;

Subianto, B ;

Marwoto, H .

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2000, 63 (3-4) :139-145

[3]

Hunt Cooke Angela, 1999, American Journal of Tropical Medicine and Hygiene, V60, P173

[4] Comparison of the OptiMAL test with PCR for diagnosis of malaria in immigrants [J].

Iqbal, J ;

Sher, A ;

Hira, PR ;

Al-Owaish, R .

JOURNAL OF CLINICAL MICROBIOLOGY, 1999, 37 (11) :3644-3646

[5] Sensitivity and specificity of dipstick tests for rapid diagnosis of malaria in nonimmune travelers [J].

Jelinek, T ;

Grobusch, MP ;

Schwenke, S ;

Steidl, S ;

von Sonnenburg, F ;

Nothdurft, HD ;

Klein, E ;

Löscher, T .

JOURNAL OF CLINICAL MICROBIOLOGY, 1999, 37 (03) :721-723

[6] Clinical features cannot predict a diagnosis of malaria or differentiate the infecting species in children living in an area of low transmission [J].

Luxemburger, C ;

Nosten, F ;

Kyle, DE ;

Kiricharoen, L ;

Chongsuphajaisiddhi, T ;

White, NJ .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1998, 92 (01) :45-49

[7] Lactate dehydrogenase and the diagnosis of malaria [J].

Makler, MT ;

Piper, RC ;

Milhous, WK .

PARASITOLOGY TODAY, 1998, 14 (09) :376-377

[8] Performance of the OptiMAL malaria antigen capture dipstick for malaria diagnosis and treatment monitoring at the Hospital for Tropical Diseases, London [J].

Moody, A ;

Hunt-Cooke, A ;

Gabbett, E ;

Chiodini, P .

BRITISH JOURNAL OF HAEMATOLOGY, 2000, 109 (04) :891-894

[9]

Moody A H, 2002, Br J Biomed Sci, V59, P228

[10] Effects of artesunate-mefloquine combination on incidence of Plasmodium falciparum malaria and mefloquine resistance in western Thailand:: a prospective study [J].

Nosten, F ;

van Vugt, M ;

Price, R ;

Luxemburger, C ;

Thway, KL ;

Brockman, A ;

McGready, R ;

ter Kuile, F ;

Looareesuwan, S ;

White, NJ .

LANCET, 2000, 356 (9226) :297-302